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The most common variant of nephrotic syndrome in children in Minimal change nephrotic syndrome. In case of MCNS, there is no need to do a renal biopsy before starting treatment. But in certain atypical features at onset, it is necessary to do a renal biopsy. They are:
Age of onset less than 12 months
Gross hematuria
Persistent microscopic hematuria
Elevated blood pressure
Low blood C3
Impaired renal function
Proteinuria despite appropriate steroid therapy
Age of onset less than 12 months
Gross hematuria
Persistent microscopic hematuria
Elevated blood pressure
Low blood C3
Impaired renal function
Proteinuria despite appropriate steroid therapy
